Effect of Cognitive Behavior Therapy on the Mental Health of Patients With Irritable Bowel Syndrome: A Systematic Review.

Irritable bowel syndrome (IBS) is a common functional gastrointestinal (GI) disorder that is frequently exacerbated by stress leading to a detrimental effect on the quality of life (QOL). This systematic review assessed the efficacy of cognitive behavioral therapy (CBT) as a therapeutic approach for irritable bowel syndrome (IBS), taking into account GI symptoms, psychological distress, sleep quality, and quality of life. Additionally, variables such as anxiety levels, depression, and inflammatory markers were assessed to provide a comprehensive evaluation of patient outcome. Database search from 2000 - 2023 yielded the identification and analysis of 12 research trials out of 1,703 articles. The studies varied in study design, participant demographics, CBT technique, intervention duration, and outcome measurement instruments. Despite variability, the majority of studies demonstrated a significant positive impact of CBT interventions on IBS. The quality of life, GI symptoms, psychological distress, and sleep disturbances all improved. However, inconsistencies in certain outcome measures and a paucity of long-term follow-up were observed in some studies. Our findings highlighted the potential of CBT as a valued therapeutic intervention for IBS, demonstrating significant improvements in various aspects of the condition.