ProofDigestwhat is actually proven
what is actually proven about the female body after forty
The archive

Six things the research keeps coming back to

For each one: how much research there is, how heavily it weighs, what women ask about it, and which treatments have actually been studied.

Skin aging

200 studies carrying the evidence · newest 2026, 84 from the last three years

5 Repeated evidence · 554 Large controlled trial · 533 Small study in people · 92

What people ask

and 47 more questions on this topic

What works, and how well it is studied

all treatments and supplements

Menopause and hormones

200 studies carrying the evidence · newest 2026, 32 from the last three years

5 Repeated evidence · 704 Large controlled trial · 1083 Small study in people · 22

What people ask

and 47 more questions on this topic

What works, and how well it is studied

all treatments and supplements

Sleep, energy and the brain

200 studies carrying the evidence · newest 2026, 80 from the last three years

5 Repeated evidence · 1054 Large controlled trial · 743 Small study in people · 21

What people ask

and 47 more questions on this topic

What works, and how well it is studied

all treatments and supplements

Hair and nails

200 studies carrying the evidence · newest 2026, 51 from the last three years

5 Repeated evidence · 564 Large controlled trial · 73 Small study in people · 137

What people ask

and 47 more questions on this topic

What works, and how well it is studied

all treatments and supplements

Living longer in good health

200 studies carrying the evidence · newest 2026, 46 from the last three years

5 Repeated evidence · 1644 Large controlled trial · 36

What people ask

and 47 more questions on this topic

What works, and how well it is studied

all treatments and supplements

The archive holds 4,693 publications, of which 1,200 were selected as carrying the evidence. How that selection works is explained on the evidence ladder.