Treatments and supplements · Isotretinoin

Can isotretinoin improve sun-damaged skin?

What we can tell you today: how thoroughly this has been studied.

Studied in controlled trials

3 studies, of which 2 are controlled trials in people with a hundred participants or more. No overview combining them yet.

4 Large controlled trial 2 studies

3 Small study in people 1 study

This says how thoroughly something has been studied — not whether it works for you. What each study actually found is in the study itself, and in the plain-language write-ups we are adding.

Appears under: Skin aging · Hair and nails

The studies

4 Large controlled trial Isotretinoin improves the appearance of photodamaged skin: results of a 36-week, multicenter, double-blind, placebo-controlled trial.
2000 · Journal of the American Academy of Dermatology · 800 participants
4 Large controlled trial Clinical panel assessment of photodamaged skin treated with isotretinoin using photographs.
1992 · Archives of dermatology · 326 participants
3 Small study in people Evaluating the combined efficacy of oral isotretinoin and topical tacrolimus versus oral finasteride and topical tacrolimus in frontal fibrosing alopecia-A randomized controlled trial.
2023 · Journal of cosmetic dermatology · 16 participants