Treatments and supplements · Probiotics for skin (oral/topical)
Can probiotics improve my skin aging?
What we can tell you today: how thoroughly this has been studied.
Studied in controlled trials
8 studies, of which 3 are controlled trials in people with a hundred participants or more. No overview combining them yet.
4 Large controlled trial 3 studies
3 Small study in people 5 studies
This says how thoroughly something has been studied — not whether it works for you. What each study actually found is in the study itself, and in the plain-language write-ups we are adding.
Appears under: Skin aging · Sleep, energy and the brain · Hair and nails
The studies
- 4 Large controlled trial
Clinical Evidence of Effects of Lactobacillus plantarum HY7714 on Skin Aging: A Randomized, Double Blind, Placebo-Controlled Study.
2016 · Journal of microbiology and biotechnology · 110 participants
- 4 Large controlled trial
Clinical evidence of benefits of a dietary supplement containing probiotic and carotenoids on ultraviolet-induced skin damage.
2011 · The British journal of dermatology · 139 participants
- 4 Large controlled trial
Effects of Heat-Killed Lactobacillus acidophilus IDCC 3302 on Skin Aging Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial in Healthy Adults.
2026 · Nutrients · 100 participants · manufacturer helped fund this
- 3 Small study in people
Effects of Lactobacillus plantarum PS128 on Depressive Symptoms and Sleep Quality in Self-Reported Insomniacs: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial.
2021 · Nutrients · manufacturer helped fund this
- 3 Small study in people
Vitamin D and probiotic co-supplementation affects mental health, hormonal, inflammatory and oxidative stress parameters in women with polycystic ovary syndrome.
2019 · Journal of ovarian research · 60 participants
- 3 Small study in people
Efficacy and Safety of Epidermidibacterium Keratini EPI-7 Derived Postbiotics in Skin Aging: A Prospective Clinical Study.
2023 · International journal of molecular sciences
- 3 Small study in people
Novel Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract provides potent skin benefits in vitro and protects skin from aging.
2024 · Journal of cosmetic dermatology
- 3 Small study in people
A Randomized Double-Blind, Placebo-Controlled Study to Evaluate the Anti-Skin-Aging Effect of LactoSporin - The Extracellular Metabolite from Bacillus coagulans ( Weizmannia coagulans ) MTCC 5856 in Healthy Female Volunteers.
2023 · Clinical, cosmetic and investigational dermatology · 56 participants