What is tibolone and does it help menopause symptoms?

What we can tell you today: how thoroughly this has been studied.

Well studied

6 studies, including 2 that bring together the results of several trials in people.

5 Repeated evidence 2 studies

4 Large controlled trial 4 studies

This says how thoroughly something has been studied — not whether it works for you. What each study actually found is in the study itself, and in the plain-language write-ups we are adding.

Appears under: Menopause and hormones

The studies

5 Repeated evidence Short-term and long-term effects of tibolone in postmenopausal women.
2016 · The Cochrane database of systematic reviews · 19,976 participants
5 Repeated evidence Short and long term effects of tibolone in postmenopausal women.
2012 · The Cochrane database of systematic reviews · 8,152 participants
4 Large controlled trial Safety and efficacy of tibolone in breast-cancer patients with vasomotor symptoms: a double-blind, randomised, non-inferiority trial.
2009 · The Lancet. Oncology · 3,148 participants
4 Large controlled trial Effects of tibolone on climacteric symptoms and quality of life in breast cancer patients--data from LIBERATE trial.
2012 · Maturitas · 3,148 participants
4 Large controlled trial Tibolone relieves climacteric symptoms in highly symptomatic women with at least seven hot flushes and sweats per day.
2005 · Maturitas · 770 participants
4 Large controlled trial Continuous combined hormone replacement therapy compared with tibolone.
1999 · Obstetrics and gynecology · 119 participants