[Effet du vernis à ongles à l'urée sur la qualité des ongles. Évaluation clinique et mesures biophysiques].
3 Petite étude chez l'humain
- Type d'étude
- essai contrôlé
- Étudié chez
- des personnes
- Participants
- 30
- Publié
- 2007 in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
- Cité
- 2 fois par d'autres recherches
- Qui a payé
- Non déclaré. PubMed ne contient pas de déclaration de conflit d'intérêts pour la plupart des articles ; ce n'est pas la même chose qu'indépendant.
- Source
- PubMed 17043834 · doi 10.1007/s00105-006-1215-7
BACKGROUND: Urea is a well-known humectant. The aim of our study was to evaluate the in vivo effect of 10% urea lacquer on nail quality. METHODS: 60 healthy probands with brittle nails were included in a randomized, controlled study. The nail lacquer was applied once (n=30) or twice daily (n=30) on one hand for 28 days, while the other hand served as untreated control. Assessments included clinical evaluations and bioengineering measurements. RESULTS: Application of the nail lacquer was well-tolerated and led to a significant clinical improvement of nail surface morphology, nail plate consistency, reflection of the nail plate surface, appearance of the cuticle and the nail fold. Sonographic nail density was slightly increased. No relevant changes were found in nail thickness and transonychial water loss. CONCLUSIONS: Nail lacquer containing urea improves the cosmetic appearance of fingernails.