Indoor PM 2.5 exposure affects skin aging manifestation in a Chinese population.
3 Small study in people
- Type of study
- clinical trial
- Studied in
- people
- Participants
- 1,003
- Published
- 2019 in Scientific reports
- Cited
- 29 times by other research
- Who paid
- Not declared. PubMed carries no conflict-of-interest statement for most articles; that is not the same as independent.
- Source
- PubMed 29127390 · doi 10.1038/s41598-017-15295-8
Traffic-related air pollution is known to be associated with skin aging manifestations. We previously found that the use of fossil fuels was associated with skin aging, but no direct link between indoor air pollutants and skin aging manifestations has ever been shown. Here we directly measured the indoor PM 2.5 exposure in 30 households in Taizhou, China. Based on the directly measured PM 2.5 exposure and questionnaire data of indoor pollution sources, we built a regression model to predict the PM 2.5 exposure in larger datasets including an initial examination group (N = 874) and a second examination group (N = 1003). We then estimated the association between the PM 2.5 exposure and skin aging manifestations by linear regression. In the initial examination group, we showed that the indoor PM 2.5 exposure levels were positively associated with skin aging manifestation, including score of pigment spots on forehead (12.5% more spots per increase of IQR, P-value 0.0371), and wrinkle on upper lip (7.7% more wrinkle on upper lip per increase of IQR, P-value 0.0218). The results were replicated in the second examination group as well as in the pooled dataset. Our study provided evidence that the indoor PM 2.5 exposure is associated with skin aging manifestation in a Chinese population.