Perte de poids et GLP-1

• 4 Essai contrôlé de grande envergure Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial.
  2024 · JAMA · 783 participants
• 4 Essai contrôlé de grande envergure Tirzepatide Once Weekly for the Treatment of Obesity.
  2022 · The New England journal of medicine · 2 539 participants
• 4 Essai contrôlé de grande envergure Once-Weekly Semaglutide in Adults with Overweight or Obesity.
  2021 · The New England journal of medicine · 1 961 participants
• 4 Essai contrôlé de grande envergure Maintien sain de la perte de poids avec exercice, liraglutide ou les deux combinés.
  2021 · The New England journal of medicine · 195 participants
• 4 Essai contrôlé de grande envergure Efficacité et sécurité de la tirzépatide une fois par semaine chez les patients japonais atteints de maladie obésité (SURMOUNT-J) : un essai de phase 3 multicentrique, randomisé, en double aveugle, contrôlé par placebo.
  2025 · The lancet. Diabetes & endocrinology · 413 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Un essai randomisé, en double aveugle et contrôlé par placébo de perte de poids utilisant la liraglutide 3,0 mg pour la récidive pondérale après un pontage gastrique à l'Y de Roux.
  2025 · Surgery for obesity and related diseases : official journal · 132 participants
• 4 Essai contrôlé de grande envergure Sécurité psychiatrique de la sémaglutide pour la gestion du poids chez les personnes sans psychopathologie majeure connue : analyse post hoc des essais STEP 1, 2, 3 et 5.
  2024 · JAMA internal medicine · 3 377 participants
• 4 Essai contrôlé de grande envergure Effet de la liraglutide 3,0 mg chez les individus obèses et atteints d'apnée obstructive du sommeil modérée ou sévère : l'essai clinique randomisé SCALE Sleep Apnea.
  2018 · International journal of obesity (2005) · 180 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Efficacité et sécurité du danuglipron (PF-06882961) chez les adultes atteints d'obésité : un essai de phase 2b randomisé, contrôlé par placébo, avec ajustement de la dose.
  2025 · Diabetes, obesity & metabolism · 628 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Comparaison des programmes d'exercice et de perte de poids basés sur la vidéo, dispensés par la télésanté, avec l'éducation en ligne sur les résultats de l'arthrose du genou : un essai randomisé.
  2022 · Annals of internal medicine · 379 participants
• 4 Essai contrôlé de grande envergure La tirzépatide et la qualité de vie liée à la santé chez les adultes en surpoids ou obèses : résultats de l'essai randomisé de phase 3 SURMOUNT-3.
  2025 · Diabetes, obesity & metabolism · 292 participants
• 4 Essai contrôlé de grande envergure Maintien du poids et perte de poids supplémentaire avec la liraglutide après une perte de poids induite par un régime hypocalorique : l'essai randomisé SCALE Maintenance.
  2014 · International journal of obesity (2005) · 422 participants
• 4 Essai contrôlé de grande envergure Liraglutide 3,0 mg et thérapie comportementale intensive (IBT) pour l'obésité en soins primaires : l'essai randomisé contrôlé SCALE IBT.
  2020 · Obesity (Silver Spring, Md.) · 142 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Temps jusqu'au plateau pondéral avec le traitement par la tirzépatide dans les essais cliniques SURMOUNT-1 et SURMOUNT-4.
  2025 · Clinical obesity · 1,438 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Un an d'exercice après la perte de poids augmente la sécrétion de GLP-1 postprandiale contrairement à l'activité habituelle ou au traitement par agoniste du récepteur GLP-1.
  2025 · Obesity (Silver Spring, Md.) · 195 participants
• 4 Essai contrôlé de grande envergure Effet d'un régime cétogène, du jeûne avec restriction de temps ou du jeûne en jours alternés sur la perte de poids chez les adultes obèses : un essai clinique randomisé.
  2025 · BMC medicine · 160 participants
• 4 Essai contrôlé de grande envergure Traitement de l'obésité et de la maladie du foie gras associée au métabolisme par un régime alimentaire ou l'orlistat : Un essai contrôlé randomisé.
  2023 · The American journal of clinical nutrition · 118 participants
• 4 Essai contrôlé de grande envergure Apitegromab for lean mass preservation during tirzepatide-induced weight loss: a randomized, double-blind, placebo-controlled phase 2 trial.
  2026 · Nature medicine · 102 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Weight reduction over time in tirzepatide-treated participants by early weight loss response: Post hoc analysis in SURMOUNT-1.
  2025 · Diabetes, obesity & metabolism · 1,545 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Effects of 4:3 Intermittent Fasting on Eating Behaviors and Appetite Hormones: A Secondary Analysis of a 12-Month Behavioral Weight Loss Intervention.
  2025 · Nutrients · 165 participants
• 4 Essai contrôlé de grande envergure Comparing Digital Therapeutic Intervention with an Intensive Obesity Management Program: Randomized Controlled Trial.
  2022 · Nutrients · 100 participants
• 4 Essai contrôlé de grande envergure Boissons édulcorées non nutritives par rapport à l'eau après un programme de gestion du poids de 52 semaines : un essai contrôlé randomisé.
  2023 · International journal of obesity (2005) · 493 participants
• 4 Essai contrôlé de grande envergure Un sommeil insuffisant prédit un mauvais maintien de la perte de poids après 1 an.
  2023 · Sleep · 195 participants
• 4 Essai contrôlé de grande envergure An Intermittent Fasting Intervention for Black Adults Can Be Feasibly Implemented in Black Churches: A Cluster Randomized Controlled Pilot Study.
  2025 · Journal of the Academy of Nutrition and Dietetics · 2,022 participants
• 4 Essai contrôlé de grande envergure Analysis of Tirzepatide Acquisition Costs and Weight Reduction Outcomes in the United Kingdom: Insights from the SURMOUNT-1 Study.
  2025 · Advances in therapy · 2,539 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Pragmatic Implementation of Online Obesity Treatment and Maintenance Interventions in Primary Care: A Randomized Clinical Trial.
  2024 · JAMA internal medicine · 540 participants
• 4 Essai contrôlé de grande envergure Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults.
  2015 · International journal of obesity (2005) · 564 participants
• 4 Essai contrôlé de grande envergure Associations between the proportion of fat-free mass loss during weight loss, changes in appetite, and subsequent weight change: results from a randomized 2-stage dietary intervention trial.
  2020 · The American journal of clinical nutrition · 209 participants
• 4 Essai contrôlé de grande envergure Evaluation of the efficacy and safety of controlled-release phentermine/topiramate in adults with obesity in Korea: A randomized, double-blind, placebo-controlled, phase 4 trial (QUEEN's study).
  2025 · Diabetes, obesity & metabolism · 232 participants
• 4 Essai contrôlé de grande envergure Five-year follow-up of a randomized weight loss trial on a digital health behaviour change support system.
  2025 · International journal of obesity (2005) · 532 participants
• 4 Essai contrôlé de grande envergure Adaptive vs Monthly Support for Weight-Loss Maintenance: A Randomized Clinical Trial.
  2025 · JAMA network open · 255 participants
• 4 Essai contrôlé de grande envergure Changes in Circulating Metabolites During Weight Loss are Associated with Adiposity Improvement, and Body Weight and Adiposity Regain During Weight Loss Maintenance: The SATIN Study.
  2022 · Molecular nutrition & food research · 162 participants
• 4 Essai contrôlé de grande envergure Community Weight Loss to Combat Obesity and Disability in At-Risk Older Adults.
  2017 · The journals of gerontology. Series A, Biological sciences a · 249 participants
• 4 Essai contrôlé de grande envergure Prospective Randomized Biomarker Study of Metformin and Lifestyle Intervention for Prevention in Obese Women at Increased Risk for Endometrial Cancer.
  2019 · Cancer prevention research (Philadelphia, Pa.) · 576 participants
• 4 Essai contrôlé de grande envergure Associations Among Stress, Internalized Weight Stigma, Emotional Eating, and Body Composition in Active-Duty Service Members Enrolling in a Randomized Controlled Trial of a Weight Management Program.
  2024 · International journal of behavioral medicine · 178 participants
• 4 Essai contrôlé de grande envergure Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial.
  1999 · JAMA · 1,187 participants
• 4 Essai contrôlé de grande envergure Screening and brief intervention for obesity in primary care: cost-effectiveness analysis in the BWeL trial.
  2020 · International journal of obesity (2005) · 1,882 participants
• 4 Essai contrôlé de grande envergure Early Weight Loss in Behavioral Treatment Predicts Later Rate of Weight Loss and Response to Pharmacotherapy.
  2020 · Annals of behavioral medicine : a publication of the Society · 170 participants
• 4 Essai contrôlé de grande envergure Does Lifestyle Intervention After Gastric Bypass Surgery Prevent Weight Regain? A Randomized Clinical Trial.
  2020 · Obesity surgery · 165 participants
• 4 Essai contrôlé de grande envergure Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity.
  2019 · Journal of obesity · 174 participants
• 4 Essai contrôlé de grande envergure Effect of Orlistat on Live Birth Rate in Overweight or Obese Women Undergoing IVF-ET: A Randomized Clinical Trial.
  2021 · The Journal of clinical endocrinology and metabolism · 439 participants
• 4 Essai contrôlé de grande envergure An internet-based platform with a low-calorie dietary intervention improves cardiometabolic risk factors in overweight and obese people in China: Half-year follow-up results of a randomized controlled trial.
  2024 · Diabetes, obesity & metabolism · 220 participants
• 4 Essai contrôlé de grande envergure Effects of Dietary Self-Monitoring, Physical Activity, Liraglutide 3.0 mg, and Placebo on Weight Loss in the SCALE IBT Trial.
  2021 · Obesity facts · 142 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure The WORD: Outcomes of a Behavioral Weight Loss Maintenance Effectiveness Trial in Rural Black Adults of Faith.
  2020 · Obesity (Silver Spring, Md.) · 440 participants
• 4 Essai contrôlé de grande envergure Efficacy and Safety of Intragastric Balloon Therapy Compared to a Multidisciplinary Weight Loss Program (OPTIFAST) in a Real-World Population: A Propensity Score Matching Analysis.
  2023 · Obesity facts · 148 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Posttraumatic Stress Disorder and Weight Loss in Male and Female Active-duty Service Members: A Weight Management Study.
  2025 · Military medicine · 178 participants
• 4 Essai contrôlé de grande envergure Tirzepatide and change in uric acid and its association with weight reduction: post hoc analyses of the SURMOUNT-1 randomised placebo-controlled trial.
  2026 · Annals of the rheumatic diseases · 2,539 participants
• 4 Essai contrôlé de grande envergure Association Between Changes in Body Composition and Physical Function After Intensive Behavioral Weight-loss Intervention: A Look AHEAD Trial Subgroup Analysis.
  2025 · The journals of gerontology. Series A, Biological sciences a · 603 participants
• 4 Essai contrôlé de grande envergure How effective is rejoining a long-term weight loss program? The 5- and 10-year MRI-assessed Follow Interventions Trial (FIT) project.
  2026 · BMC medicine · 572 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Fetuin-B, a potential link of liver-adipose tissue cross talk during diet-induced weight loss-weight maintenance.
  2021 · Nutrition & diabetes · 143 participants
• 4 Essai contrôlé de grande envergure The Effect of Different Types of Monitoring Strategies on Weight Loss: A Randomized Controlled Trial.
  2018 · Obesity (Silver Spring, Md.) · 171 participants
• 4 Essai contrôlé de grande envergure Short- and Long-Term Changes in Health-Related Quality of Life with Weight Loss: Results from a Randomized Controlled Trial.
  2019 · Obesity (Silver Spring, Md.) · 137 participants
• 4 Essai contrôlé de grande envergure TCF7L2 genetic variants modulate the effect of dietary fat intake on changes in body composition during a weight-loss intervention.
  2013 · The American journal of clinical nutrition · 591 participants
• 4 Essai contrôlé de grande envergure Web-Based Interventions Alone or Supplemented with Peer-Led Support or Professional Email Counseling for Weight Loss and Weight Maintenance in Women from Rural Communities: Results of a Clinical Trial.
  2018 · Journal of obesity · 301 participants
• 4 Essai contrôlé de grande envergure The Impact of Timing of Exercise Initiation on Weight Loss: An 18-Month Randomized Clinical Trial.
  2020 · Obesity (Silver Spring, Md.) · 170 participants
• 4 Essai contrôlé de grande envergure Nonsurgical weight loss for extreme obesity in primary care settings: results of the Louisiana Obese Subjects Study.
  2010 · Archives of internal medicine · 200 participants
• 4 Essai contrôlé de grande envergure Exploring the effectiveness of an 18-month weight management intervention in adults with Down syndrome using propensity score matching.
  2021 · Journal of intellectual disability research : JIDR · 124 participants
• 4 Essai contrôlé de grande envergure Associations between reliable changes in depression and changes in BMI, total body fatness and visceral adiposity during a 12-month weight loss trial.
  2020 · International journal of obesity (2005) · 298 participants
• 4 Essai contrôlé de grande envergure Randomized controlled trial of financial incentives during weight-loss induction and maintenance in online group weight control.
  2022 · Obesity (Silver Spring, Md.) · 418 participants
• 4 Essai contrôlé de grande envergure Effects of a Web-Based Weight Loss Program on the Healthy Eating Index-NVS in Adults with Overweight or Obesity and the Association with Dietary, Anthropometric and Cardiometabolic Variables: A Randomized Controlled Clinical Trial.
  2023 · Nutrients · 153 participants
• 4 Essai contrôlé de grande envergure Regular Consumption of Lipigo ® Promotes the Reduction of Body Weight and Improves the Rebound Effect of Obese People Undergo a Comprehensive Weight Loss Program.
  2021 · Nutrients · 120 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Impact of a Weight Management Intervention on Eating Competence: Importance of Measurement Interval in Protocol Design.
  2019 · American journal of health promotion : AJHP · 101 participants
• 4 Essai contrôlé de grande envergure Weight management for overweight and obese men delivered through professional football clubs: a pilot randomized trial.
  2014 · The international journal of behavioral nutrition and physic · 103 participants
• 4 Essai contrôlé de grande envergure A family and community focused lifestyle program prevents weight regain in Pacific Islanders: a pilot randomized controlled trial.
  2012 · Health education & behavior : the official publication of th · 144 participants
• 4 Essai contrôlé de grande envergure Effect of orlistat on weight regain and cardiovascular risk factors following a very-low-energy diet in abdominally obese patients: a 3-year randomized, placebo-controlled study.
  2007 · Diabetes care · 383 participants
• 4 Essai contrôlé de grande envergure Implementing weight maintenance with existing staff and electronic health record tools in a primary care setting: Baseline results from the MAINTAIN PRIME trial.
  2024 · Contemporary clinical trials · 269 participants
• 4 Essai contrôlé de grande envergure Weight loss maintenance following an augmented intervention for early slow weight loss responders: An adaptive trial.
  2024 · Translational behavioral medicine · 174 participants
• 4 Essai contrôlé de grande envergure Choosing Health: acceptability and feasibility of a theory-based, online-delivered, tailored weight loss, and weight loss maintenance intervention.
  2024 · Translational behavioral medicine · 288 participants
• 4 Essai contrôlé de grande envergure Efficacy and safety of liraglutide 3.0 mg for weight management are similar across races: subgroup analysis across the SCALE and phase II randomized trials.
  2016 · Diabetes, obesity & metabolism · 5,325 participants
• 4 Essai contrôlé de grande envergure Regular self-weighing to promote weight maintenance after intentional weight loss: a quasi-randomized controlled trial.
  2015 · Journal of public health (Oxford, England) · 3,290 participants
• 4 Essai contrôlé de grande envergure Efficacy and Safety of Lipase Inhibitor Orlistat in Japanese with Excessive Visceral Fat Accumulation: 24-Week, Double-Blind, Randomized, Placebo-Controlled Study.
  2020 · Advances in therapy · 100 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Long-term weight maintenance after a 17-week weight loss intervention with or without a one-year maintenance program: a randomized controlled trial.
  2015 · Journal of obesity · 201 participants
• 4 Essai contrôlé de grande envergure The challenge of a 2-year follow-up after intervention for weight loss in primary care.
  2015 · International journal of obesity (2005) · 203 participants
• 4 Essai contrôlé de grande envergure Tirzepatide Efficacy and Tolerability According to Early Weight Response: A Post Hoc Analysis of the SURMOUNT-1 and SURMOUNT-2 Trials.
  2026 · Diabetes, obesity & metabolism · 2,384 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Wearable-Measured Physical Activity Goal Adherence and Body Composition Change in a 12-Month mHealth Weight Loss Trial.
  2026 · Sensors (Basel, Switzerland) · 502 participants
• 4 Essai contrôlé de grande envergure Semaglutide Injection Once-Weekly for Weight Management in Adults: Results From A Randomized Phase III, Active-Controlled Study.
  2026 · Diabetes, obesity & metabolism · 270 participants · le fabricant a aidé à financer ceci
• 4 Essai contrôlé de grande envergure Tirzepatide compared with semaglutide in obesity disease: a subpopulation analysis applying Japan Society for the Study of Obesity criteria in the global SURMOUNT-5 trial.
  2026 · Current medical research and opinion · 750 participants
• 4 Essai contrôlé de grande envergure Racial disparities in the efficacy of traditional versus acceptance-based behavioral weight loss.
  2026 · Health psychology : official journal of the Division of Heal · 737 participants
• 4 Essai contrôlé de grande envergure Development, Challenges, and Evolution of the Log2Lose Intervention for Weight Management: Randomized Controlled Digital Health Trial.
  2025 · JMIR formative research · 706 participants
• 4 Essai contrôlé de grande envergure Orlistat, a lipase inhibitor, for weight maintenance after conventional dieting: a 1-y study.
  1999 · The American journal of clinical nutrition · 729 participants

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