[From the Cochrane Library: Improvement of photodamaged skin with retinoid creams and not with other local treatments].
5 Repeated evidence
What this means for you: this is established.
- Type of study
- meta-analysis or systematic review
- Studied in
- people
- Participants
- not stated in the abstract
- Published
- 2006 in Nederlands tijdschrift voor geneeskunde
- Cited
- 0 times by other research
- Who paid
- Not declared. PubMed carries no conflict-of-interest statement for most articles; that is not the same as independent.
- Source
- PubMed 16463616
The plain-language write-up of this study is still being written.
Below is the abstract exactly as the researchers published it.
Abstract by the researchers — original text
A Cochrane systematic review of 30 randomised clinical trials assessed the effects of current treatments for adults with mild-to-severe changes in facial and forearm skin that occurred as a result of prolonged exposure to the sun ('photodamage'). Topical tretinoin > or = 0.02% improved the appearance of mild-to-severe photodamage. Tazarotene 0.01-0.1% and isotretinoin 0.1% provided benefit to patients with moderate photodamage. The treatment duration was 4-11 months. Adverse effects were pain and redness. Both the efficacy and adverse effects were dose-dependent. Other treatments, such as polysaccharides, hydroxy acids, surgical procedures and laser, cannot be recommended.