Treatments and supplements · Niacinamide
What does niacinamide actually do?
What we can tell you today: how thoroughly this has been studied.
Studied in controlled trials
3 studies, of which 1 is a controlled trial in people with a hundred participants or more. No overview combining them yet.
4 Large controlled trial 1 study
3 Small study in people 2 studies
This says how thoroughly something has been studied — not whether it works for you. What each study actually found is in the study itself, and in the plain-language write-ups we are adding.
Appears under: Skin aging
The studies
- 4 Large controlled trial
A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen.
2010 · The British journal of dermatology · 196 participants
- 3 Small study in people
Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing: A Double-blind, Randomised, Placebo-controlled Clinical Study.
2025 · Current medicinal chemistry
- 3 Small study in people
Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy.
2021 · Journal of cosmetic dermatology · manufacturer helped fund this