Treatments and supplements · Equol (S-equol supplement)

Does equol help with hot flashes?

What we can tell you today: how thoroughly this has been studied.

Well studied

4 studies, including one that brings together the results of several trials in people.

5 Repeated evidence 1 study

4 Large controlled trial 1 study

3 Small study in people 2 studies

This says how thoroughly something has been studied — not whether it works for you. What each study actually found is in the study itself, and in the plain-language write-ups we are adding.

Appears under: Menopause and hormones

The studies

5 Repeated evidence Equol Decreases Hot Flashes in Postmenopausal Women: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
2019 · Journal of medicinal food
4 Large controlled trial A pilot study on the effects of S-equol compared to soy isoflavones on menopausal hot flash frequency.
2012 · Journal of women's health (2002) · 102 participants
3 Small study in people Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study.
2017 · Maturitas
3 Small study in people Effects of an equol-containing supplement on advanced glycation end products, visceral fat and climacteric symptoms in postmenopausal women: A randomized controlled trial.
2021 · PloS one · manufacturer helped fund this