Topic

Skin aging

The 55 studies that carry the evidence on this topic, ordered by weight: the stronger the evidence and the more the study was built on, the higher it stands.

all levels level 5 · 55 level 4 · 53 level 3 · 92

5 Repeated evidence A systematic review of natural products for skin applications: Targeting inflammation, wound healing, and photo-aging.
2023 · Phytomedicine : international journal of phytotherapy and ph
5 Repeated evidence Defining skin aging and its risk factors: a systematic review and meta-analysis.
2022 · Scientific reports
5 Repeated evidence Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis.
2023 · Nutrients · 1,721 participants
5 Repeated evidence Comparing Tretinoin to Other Topical Therapies in the Treatment of Skin Photoaging: A Systematic Review.
2024 · American journal of clinical dermatology
5 Repeated evidence The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series.
2025 · Medicina (Kaunas, Lithuania)
5 Repeated evidence Dietary interventions in skin ageing: a systematic review and meta-analysis.
2025 · Journal of physiological anthropology · manufacturer helped fund this
5 Repeated evidence Evaluating the effectiveness and safety of radiofrequency for face and neck rejuvenation: A systematic review.
2022 · Lasers in surgery and medicine
5 Repeated evidence Cosmeceuticals in photoaging: A review.
2024 · Skin research and technology : official journal of Internati
5 Repeated evidence Skin measurement devices to assess skin quality: A systematic review on reliability and validity.
2022 · Skin research and technology : official journal of Internati · 3,172 participants
5 Repeated evidence Sirtuin 1 and Skin: Implications in Intrinsic and Extrinsic Aging-A Systematic Review.
2021 · Cells · 46 participants
5 Repeated evidence Home-based devices in dermatology: a systematic review of safety and efficacy.
2022 · Archives of dermatological research
5 Repeated evidence Efficacy of topical vitamin C in melasma and photoaging: A systematic review.
2023 · Journal of cosmetic dermatology · 139 participants
5 Repeated evidence Microfocused Ultrasound With Visualization (MFU-V) Effectiveness and Safety: A Systematic Review and Meta-Analysis.
2025 · Aesthetic surgery journal · 785 participants
5 Repeated evidence Efficacy, Durability, and Safety of Collagen Biostimulators Based on Poly-L-Lactic Acid (PLLA) and Calcium Hydroxyapatite (CaHA) in the Face: A Systematic Review.
2026 · Aesthetic plastic surgery
5 Repeated evidence Comparative efficacy of topical interventions for facial photoaging: a network meta-analysis.
2025 · Scientific reports · 3,905 participants
5 Repeated evidence Cosmeceuticals for antiaging: a systematic review of safety and efficacy.
2024 · Archives of dermatological research · 1,236 participants
5 Repeated evidence Intense Pulsed Light on skin rejuvenation: a systematic review.
2022 · Archives of dermatological research · 637 participants
5 Repeated evidence Tissue Fillers for the Nasolabial Fold Area: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
2021 · Aesthetic plastic surgery
5 Repeated evidence Rejuvenating the periorbital area using platelet-rich plasma: a systematic review and meta-analysis.
2022 · Archives of dermatological research · 455 participants
5 Repeated evidence Systematic review and meta-analysis of randomized clinical trials comparing efficacy, safety, and satisfaction between ablative and non-ablative lasers in facial and hand rejuvenation/resurfacing.
2022 · Lasers in medical science · 124 participants
5 Repeated evidence Collagen supplementation for skin health: A mechanistic systematic review.
2021 · Journal of cosmetic dermatology
5 Repeated evidence Novel approaches for managing aged skin and nonmelanoma skin cancer.
2021 · Advanced drug delivery reviews
5 Repeated evidence Botulinum toxin type A for facial wrinkles.
2021 · The Cochrane database of systematic reviews · 1,471 participants
5 Repeated evidence Treatment of Solar Lentigines: A Systematic Review of Clinical Trials.
2025 · Journal of cosmetic dermatology · 3,234 participants
5 Repeated evidence Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.
2025 · Indian journal of dermatology, venereology and leprology · 646 participants
5 Repeated evidence Exploring the Role of Herbal Compounds in Skin Aging: A Systematic Review of Topical Approaches.
2025 · Phytotherapy research : PTR
5 Repeated evidence Systematic Review of Platelet-Rich Plasma and Platelet-Rich Fibrin in Facial Rejuvenation.
2025 · Annals of plastic surgery · 514 participants
5 Repeated evidence The selection of hyaluronic acid when treating with the nasolabial fold: A meta-analysis.
2022 · Journal of cosmetic dermatology · 1,190 participants
5 Repeated evidence A Systematic Review of the Efficacy and Safety of Profhilo® and Profhilo® Body.
2026 · Plastic and aesthetic nursing · 278 participants
5 Repeated evidence The Effects of Facial Lipografting on Skin Quality: A Systematic Review.
2020 · Plastic and reconstructive surgery · 301 participants
5 Repeated evidence Appearance-based interventions to reduce ultraviolet exposure and/or increase sun protection intentions and behaviours: a systematic review and meta-analyses.
2013 · British journal of health psychology
5 Repeated evidence Intrinsic and extrinsic risk factors for sagging eyelids.
2014 · JAMA dermatology
5 Repeated evidence Optical Coherence Tomography Imaging of Normal, Chronologically Aged, Photoaged and Photodamaged Skin: A Systematic Review.
2015 · Dermatologic surgery : official publication for American Soc
5 Repeated evidence Efficacy and Safety of Centella Asiatica ( L. ) Urb. on Wrinkles: A Systematic Review of Published Data and Network Meta-Analysis.
2021 · Journal of cosmetic science
5 Repeated evidence The efficacy of various interventions as good strategies to reduce pain in botulinum neurotoxin A for wrinkles. A systematic review of the randomized controlled trials (RCTs).
2024 · Journal of cosmetic and laser therapy : official publication
5 Repeated evidence Light-Emitting Diode-Based Photodynamic Therapy for Photoaging, Scars, and Dyspigmentation: A Systematic Review.
2021 · Dermatologic surgery : official publication for American Soc
5 Repeated evidence Facial Wrinkles in Europeans: A Genome-Wide Association Study.
2019 · The Journal of investigative dermatology
5 Repeated evidence Optimizing Collagen Biostimulator Choice in LATAM: Expert Consensus on Patient Selection, Ethnic Skin Phenotypes, and Accessibility.
2025 · Journal of cosmetic dermatology
5 Repeated evidence Cosmetic Botulinum Toxin A Injections to the Upper Face: A Systematic Review and Meta-Analysis of Clinical Studies.
2026 · Journal of cosmetic dermatology
5 Repeated evidence Efficacy of formulations for treating hyperpigmentation: a systematic review and meta-analysis.
2025 · Archives of dermatological research · 337 participants
5 Repeated evidence Astragalus membranaceus Extract as a Botanical Ingredient for Pigmentary and Anti-Aging Skincare: A Systematic Review.
2026 · Journal of drugs in dermatology : JDD
5 Repeated evidence Effects of GLP-1 Receptor Agonists on Skin Quality: A Comprehensive Literature Review.
2026 · Aesthetic plastic surgery
5 Repeated evidence Clinical Advances in Exosome-Based Therapies for Aesthetic Medicine: A Systematic Review and Meta-analysis of Human Clinical Trials.
2026 · Aesthetic surgery journal
5 Repeated evidence Efficacy and Safety of Amino Acid-Enriched Hyaluronic Acid in Facial Rejuvenation: A Systematic Review and Meta-Analysis.
2026 · Journal of cosmetic dermatology · 11 participants
5 Repeated evidence Laser Resurfacing at the Time of Facelift Surgery: A Systematic Review and Meta-Analysis.
2026 · Aesthetic surgery journal · 1,361 participants
5 Repeated evidence Beyond Wrinkles: A Systematic Review and Meta-analysis of Off-Label Aesthetic Uses of Botulinum Neurotoxin.
2026 · Annals of plastic surgery · 1,903 participants
5 Repeated evidence What influences the uptake of information to prevent skin cancer? A systematic review and synthesis of qualitative research.
2010 · Health education research
5 Repeated evidence Can dietary intake influence perception of and measured appearance? A systematic review.
2015 · Nutrition research (New York, N.Y.) · 4,741 participants
5 Repeated evidence SUPPLEMENT ARTICLE: Scientific and Clinical Insights into the Facial Application of Mineralizing Volcanic Water.
2022 · Journal of drugs in dermatology : JDD
5 Repeated evidence The Preventive Value of Sun Protection.
2022 · Current problems in dermatology · 1,621 participants
5 Repeated evidence How effective are physical appearance interventions in changing smoking perceptions, attitudes and behaviours? A systematic review.
2013 · Tobacco control
5 Repeated evidence Hypo-collagenesis in photoaged skin predicts response to anti-aging cosmeceuticals.
2014 · Journal of cosmetic dermatology · 20 participants
5 Repeated evidence Photoprotective effect of botanicals and vitamins: A systematic review of clinical trials.
2016 · The Journal of dermatological treatment
5 Repeated evidence [From the Cochrane Library: Improvement of photodamaged skin with retinoid creams and not with other local treatments].
2006 · Nederlands tijdschrift voor geneeskunde
5 Repeated evidence Effect of tretinoin emollient cream on photodamaged skin: relationship between clinical improvement and skin irritation.
1996 · The British journal of dermatology