Topic

Menopause and hormones

The 70 studies that carry the evidence on this topic, ordered by weight: the stronger the evidence and the more the study was built on, the higher it stands.

all levels level 5 · 70 level 4 · 108 level 3 · 22

5 Repeated evidence Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence.
2019 · Lancet (London, England)
5 Repeated evidence Mapping global prevalence of menopausal symptoms among middle-aged women: a systematic review and meta-analysis.
2024 · BMC public health
5 Repeated evidence Systematic review and meta-analysis of the effects of menopause hormone therapy on cognition.
2024 · Frontiers in endocrinology
5 Repeated evidence Quality of life in postmenopausal women with osteoporosis: a systematic review and meta-analysis.
2023 · Quality of life research : an international journal of quali
5 Repeated evidence Effect of Soy Isoflavones on Measures of Estrogenicity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
2025 · Advances in nutrition (Bethesda, Md.) · 3,285 participants · manufacturer helped fund this
5 Repeated evidence Effects of mind-body exercise on perimenopausal and postmenopausal women: a systematic review and meta-analysis.
2024 · Menopause (New York, N.Y.) · 1,005 participants
5 Repeated evidence Long-term hormone therapy for perimenopausal and postmenopausal women.
2017 · The Cochrane database of systematic reviews · 43,637 participants
5 Repeated evidence Guidelines for the Evaluation and Treatment of Perimenopausal Depression: Summary and Recommendations.
2020 · Journal of women's health (2002)
5 Repeated evidence Fezolinetant and Elinzanetant Therapy for Menopausal Women Experiencing Vasomotor Symptoms: A Systematic Review and Meta-analysis.
2025 · Obstetrics and gynecology · 4,087 participants
5 Repeated evidence Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause : A Systematic Review.
2024 · Annals of internal medicine
5 Repeated evidence Vasomotor symptoms and risk of cardiovascular disease in peri- and postmenopausal women: A systematic review and meta-analysis.
2023 · Maturitas · 11 participants
5 Repeated evidence A systematic review and critical appraisal of menopause guidelines.
2024 · BMJ sexual & reproductive health · manufacturer helped fund this
5 Repeated evidence Global view of vasomotor symptoms and sleep disturbance in menopause: a systematic review.
2023 · Climacteric : the journal of the International Menopause Soc · 27 participants
5 Repeated evidence The Effect of Vitamin E Supplementation in Postmenopausal Women-A Systematic Review.
2023 · Nutrients
5 Repeated evidence Effects of Omega-3 Polyunsaturated Fatty Acids Intake on Vasomotor Symptoms, Sleep Quality and Depression in Postmenopausal Women: A Systematic Review.
2023 · Nutrients
5 Repeated evidence Exploring symptom clusters across the menopausal stages - systematic review and meta-analysis.
2025 · Sexual & reproductive healthcare : official journal of the S · 14,760 participants
5 Repeated evidence Vaginal estrogen therapy for treatment of menopausal genitourinary syndrome among breast cancer survivors: a systematic review and meta-analysis.
2025 · Revista brasileira de ginecologia e obstetricia : revista da
5 Repeated evidence Equol Decreases Hot Flashes in Postmenopausal Women: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
2019 · Journal of medicinal food
5 Repeated evidence Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis.
2006 · JAMA
5 Repeated evidence Effects of nutritional interventions on the severity of depressive and anxiety symptoms of women in the menopausal transition and menopause: a systematic review, meta-analysis, and meta-regression.
2022 · Menopause (New York, N.Y.) · 16 participants
5 Repeated evidence Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes.
2005 · The Cochrane database of systematic reviews · manufacturer helped fund this
5 Repeated evidence Resistance training for postmenopausal women: systematic review and meta-analysis.
2022 · Menopause (New York, N.Y.) · 452 participants
5 Repeated evidence Hormone Therapy and Other Treatments for Symptoms of Menopause.
2017 · American family physician
5 Repeated evidence Neurokinin 1/3 receptor antagonists for menopausal women: A current systematic review and insights into the investigational non-hormonal therapy.
2023 · Medicine · 1,993 participants
5 Repeated evidence Estimation of placebo effect in randomized placebo-controlled trials for moderate or severe vasomotor symptoms: a meta-analysis.
2022 · Menopause (New York, N.Y.)
5 Repeated evidence Short-term and long-term effects of tibolone in postmenopausal women.
2016 · The Cochrane database of systematic reviews · 19,976 participants
5 Repeated evidence Systematic review of neurokinin-3 receptor antagonists for the management of vasomotor symptoms of menopause.
2024 · Menopause (New York, N.Y.)
5 Repeated evidence Cognitive behavioural therapy for menopausal symptoms: a systematic review of efficacy in improving quality of life.
2026 · BMC women's health · 910 participants
5 Repeated evidence Complementary therapies for management of menopausal symptoms: a systematic review to inform the update of the International Menopause Society recommendations on women's midlife health.
2026 · Climacteric : the journal of the International Menopause Soc
5 Repeated evidence Black cohosh (Cimicifuga spp.) for menopausal symptoms.
2012 · The Cochrane database of systematic reviews · 468 participants
5 Repeated evidence Using ginseng for menopausal women's health care: A systematic review of randomized placebo-controlled trials.
2022 · Complementary therapies in clinical practice · 515 participants
5 Repeated evidence Vasomotor symptoms resulting from natural menopause: a systematic review and network meta-analysis of treatment effects from the National Institute for Health and Care Excellence guideline on menopause.
2018 · BJOG : an international journal of obstetrics and gynaecolog · 8,326 participants
5 Repeated evidence Efficacy of Low-Dose Paroxetine for the Treatment of Hot Flushes in Surgical and Physiological Postmenopausal Women: Systematic Review and Meta-Analysis of Randomized Trials.
2020 · Medicina (Kaunas, Lithuania)
5 Repeated evidence Comparing Interventions for Management of Hot Flashes in Patients With Breast and Prostate Cancer: A Systematic Review With Meta-Analyses.
2021 · Oncology nursing forum · manufacturer helped fund this
5 Repeated evidence Efficacy of mind-body therapies and exercise-based interventions on menopausal-related outcomes among Asian perimenopause women: A systematic review, meta-analysis, and synthesis without a meta-analysis.
2021 · Journal of advanced nursing
5 Repeated evidence Recommended measurement instruments for menopausal vasomotor symptoms: the COMMA (Core Outcomes in Menopause) consortium.
2024 · Menopause (New York, N.Y.) · 36 participants · manufacturer helped fund this
5 Repeated evidence Efficacy of plant-derived dietary supplements in improving overall menopausal symptoms in women: An updated systematic review and meta-analysis.
2024 · Phytotherapy research : PTR · 28 participants
5 Repeated evidence Use of interventions involving virtual reality tasks during the climacteric: a systematic review.
2022 · Climacteric : the journal of the International Menopause Soc
5 Repeated evidence The bidirectional relationship between vasomotor symptoms and depression across the menopausal transition: a systematic review of longitudinal studies.
2018 · Menopause (New York, N.Y.) · 10,008 participants
5 Repeated evidence The efficacy and tolerability of SSRI/SNRIs in the treatment of vasomotor symptoms in menopausal women: a systematic review.
2016 · Journal of the American Association of Nurse Practitioners
5 Repeated evidence The impact of cannabis use on vasomotor symptoms, mood, insomnia and sexuality in perimenopausal and postmenopausal women: a systematic review.
2022 · Climacteric : the journal of the International Menopause Soc
5 Repeated evidence Gabapentin for the treatment of hot flushes in menopause: a meta-analysis.
2020 · Menopause (New York, N.Y.)
5 Repeated evidence Acupuncture for menopausal hot flushes.
2013 · The Cochrane database of systematic reviews · 1,155 participants
5 Repeated evidence Dehydroepiandrosterone for women in the peri- or postmenopausal phase.
2017 · The Cochrane database of systematic reviews · 376 participants
5 Repeated evidence Chinese herbal medicine for menopausal symptoms.
2016 · The Cochrane database of systematic reviews · 2,902 participants
5 Repeated evidence NIH State-of-the-Science Conference Statement on management of menopause-related symptoms.
2007 · NIH consensus and state-of-the-science statements
5 Repeated evidence Testosterone use for hypoactive sexual desire disorder in postmenopausal women.
2023 · Menopause (New York, N.Y.)
5 Repeated evidence Does aromatherapy with lavender affect physical and psychological symptoms of menopausal women? A systematic review and meta-analysis.
2020 · Complementary therapies in clinical practice · 493 participants
5 Repeated evidence Mind-body interventions for vasomotor symptoms in healthy menopausal women and breast cancer survivors. A systematic review.
2018 · Journal of psychosomatic obstetrics and gynaecology · 7 participants
5 Repeated evidence Commonly used types of postmenopausal estrogen for treatment of hot flashes: scientific review.
2004 · JAMA
5 Repeated evidence Can massage ameliorate menopausal and postmenopausal symptoms in women? A systematic review and meta-analysis.
2026 · Complementary therapies in medicine
5 Repeated evidence Is hypertension negatively associated with memory performance in women during climacteric? A systematic review.
2025 · BMC women's health
5 Repeated evidence A systematic review of heart rate variability and menopausal vasomotor symptoms.
2026 · Physiological reports
5 Repeated evidence The effectiveness of red clover on hot-flash in menopausal women: a GRADE-assessed systematic review and meta-analysis.
2026 · European journal of obstetrics, gynecology, and reproductive
5 Repeated evidence Kuntai capsule for the treatment of menopausal symptoms induced by GnRH-a therapy: A systematic review and meta-analysis of randomized controlled trials.
2025 · Journal of ethnopharmacology · 3,577 participants
5 Repeated evidence The use of conjugated estrogens and bazedoxifene for the management of vasomotor symptoms in premenopausal and menopausal patients with endometriosis: a systematic review.
2026 · Climacteric : the journal of the International Menopause Soc
5 Repeated evidence Genetic Variation and Hot Flashes: A Systematic Review.
2021 · The Journal of clinical endocrinology and metabolism · 500 participants
5 Repeated evidence N-3 Polyunsatured Fatty Acids in Menopausal Transition: A Systematic Review of Depressive and Cognitive Disorders with Accompanying Vasomotor Symptoms.
2018 · International journal of molecular sciences
5 Repeated evidence The efficacy of purified pollen extract for reducing vasomotor symptoms in women: a systematic review and meta-analysis.
2024 · Menopause (New York, N.Y.) · 420 participants
5 Repeated evidence Psychoeducational interventions to alleviate hot flashes: a systematic review.
2008 · Menopause (New York, N.Y.) · 475 participants
5 Repeated evidence Therapeutic options for the management of hot flashes in breast cancer survivors: an evidence-based review.
2007 · Clinical therapeutics
5 Repeated evidence Efficacy of Cimicifuga racemosa, Hypericum perforatum and Agnus castus in the treatment of climacteric complaints: a systematic review.
2013 · Gynecological endocrinology : the official journal of the In
5 Repeated evidence Limitations in functioning in climacteric syndrome: a systematic literature review using the ICF.
2022 · Climacteric : the journal of the International Menopause Soc
5 Repeated evidence The Effect of Transdermal Estrogen Patch Use on Cardiovascular Outcomes: A Systematic Review.
2018 · Journal of women's health (2002)
5 Repeated evidence Short and long term effects of tibolone in postmenopausal women.
2012 · The Cochrane database of systematic reviews · 8,152 participants
5 Repeated evidence Efficacy and safety of desvenlafaxine treatment for hot flashes associated with menopause: a meta-analysis of randomized controlled trials.
2014 · Gynecologic and obstetric investigation
5 Repeated evidence Clinical Inquiries: Does exercise relieve vasomotor menopausal symptoms?
2019 · The Journal of family practice
5 Repeated evidence Confirmation of the efficacy of ERr 731 in perimenopausal women with menopausal symptoms.
2009 · Alternative therapies in health and medicine · 56 participants
5 Repeated evidence Comparison of efficacy and local tolerability of estradiol metered-dose transdermal spray to estradiol patch in a network meta-analysis.
2017 · Climacteric : the journal of the International Menopause Soc
5 Repeated evidence Effects of low-dose norethindrone acetate plus ethinyl estradiol (0.5 mg/2.5 microg) in women with postmenopausal symptoms: updated analysis of three randomized, controlled trials.
2006 · Clinical therapeutics · 1,265 participants